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Practical guideline for the management of allergic rhinitis in Japan 2024

  • Mitsuhiro Okano
  • , Kimihiro Okubo
  • , Minoru Gotoh
  • , Mikiya Asako
  • , Nobuo Ohta
  • , Atsushi Kamijo
  • , Kayoko Kawashima
  • , Masafumi Sakashita
  • , Daiju Sakurai
  • , Tetsuya Terada
  • , Yuji Nakamaru
  • , Takechiyo Yamada
  • , Shuji Yonekura
  • , Aiko Oka
  • , Marie Yamada
  • , Tomokazu Yoshizaki
  • International University of Health and Welfare
  • Nippon Medical School
  • Kansai Medical University
  • Tohoku Pharmaceutical University
  • Kamijo Allergy & ENT Clinic
  • Osaka Habikino Medical Center
  • University of Yamanashi
  • Osaka Medical College
  • Faculty of Medicine
  • Akita University
  • Chiba University School of Medicine
  • Kanazawa University

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

The Practical Guideline for the Management of Allergic Rhinitis in Japan was first published in 1993. After the COVID-19 pandemic, the current 10th edition was published in 2024. The most recent collection of evidence from the literature, such as the sustained post-treatment effect of sublingual immunotherapy on Japanese cedar pollinosis, was added to the revised guideline, which incorporates evidence-based medicine. In this revised guideline, a diagram illustrating the pathogenesis of allergic rhinitis and the mechanisms of action of various pharmacological treatments has been added. Also included is a diagram that shows the mechanism of action of allergen immunotherapy and a more detailed description of the oral allergy syndrome. The clinical question and answer section was also revised along with the introduction of new questions, such as: Does anti-IgE antibody treatment effectively reduce the symptoms of severe seasonal allergic rhinitis? Also updated was the evidence-based step-by-step strategy for treatment.

Original languageEnglish
Pages (from-to)426-441
Number of pages16
JournalAuris Nasus Larynx
Volume52
Issue number4
DOIs
StatePublished - Aug 2025

Keywords

  • Allergic rhinitis
  • Guideline
  • Mechanism of action of pharmacotherapy
  • Pollinosis
  • Sublingual immunotherapy

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